Different critical points of chiral and deconfinement phase transitions in (2+1)-dimensional fermion-gauge interacting model

Based on the truncated Dyson-Schwinger equations for fermion and massive boson propagators in QED$_3$, the fermion chiral condensate and the mass singularities of the fermion propagator via the Schwinger function are investigated. It is shown that the critical point of chiral phase transition is apparently different from that of deconfinement phase transition and in Nambu phase the fermion is confined only for small gauge boson mass.Comment: 5 Pages and 3 figure

Effect of quercetin on biochemical parameters in letrozoleinduced polycystic ovary syndrome in rats

Purpose: To investigate the effect of quercetin, a natural flavonoid, on biochemical parameters in letrozole-induced polycystic ovary syndrome (PCOS) in ratsMethods: Oral glucose test was performed with the aid of a glucometer. Estradiol, testosterone and steroidogenic enzyme activities were determined using standard protocols. Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) activities were determined by standard methods. Histological analysis was carried out with haematoxylin and eosin (H&E) staining.Results: Quercetin exerted protective effects against PCOS in the rat model by enhancing the levels of antioxidant enzymes, viz, CAT, SOD and GPX. Quercetin also prevented weight gain, and caused significant decline in serum glucose levels in PCOS rats. Furthermore, quercetin normalised estradiol and testosterone levels, as well t steroidogenic enzyme activities, but blocked letrozole-induced abnormalities in PCOS. It also exerted protective effects on the anatomy of the ovaries.Conclusion: These results indicate that quercetin exerts protective effects on letrozole-induced PCOS in rats. Thus, quercetin may be an important lead molecule for the treatment of PCOSKeywords: Letrozole, Quercetin, Polycystic ovary syndrome, Oxidative stress, Steroidogenic enzyme

Seasonal variation of thermal sensations in residential buildings in the hot summer and cold winter zone of China

The seasonal differences of neutral or acceptable temperatures between summer and winter were revealed by previous researchers, but the studies on the difference of human thermal adaption in transitional seasons are insufficient. To clarify this, this paper analyzes the data from a nationwide field study database, including a year-long survey which was carried out in 505 residential buildings in six cities located in the Hot Summer and Cold Winter (HSCW) zone of China involving 11,524 subjects. Results show a significant difference of adaptive responses in different seasons. Air temperature is found to be the most significant driver for behavioral responses, and a lag of behavioral responses behind climate change in transitional seasons is observed. Occupants not only adjust clothing insulation according to air temperature in different seasons, but also actively control indoor air movement, including closing/opening windows and using fans. The seasonal, monthly and daily neutral temperatures are studied, implying that occupants’ thermal experience history has significant effect on their thermal comfort by behavioral, physiological and psychological paths. Thus, the running mean air temperature method and aPMV model are recommended for thermal comfort evaluation in free-running space. The research results provide comprehensive understanding of the thermal comfort demand which directly affects the energy needs for heating and cooling purpose. The findings provide scientific evidence to the concept that dynamic thermal comfort temperature range should be considered in the evaluation of indoor thermal environment

SPECIAL VALUES OF THE BELL POLYNOMIALS OF THE SECOND KIND FOR SOME SEQUENCES AND FUNCTIONS: Special values of Bell polynomials of second kind

In the paper, the authors concisely review some closed formulas and applications of special values of the Bell polynomials of the second kind for some special sequences and elementary functions, explicitly present closed formulas for those sequences investigated in [F. T. Howard, A special class of Bell polynomials, Math. Comp. 35 (1980), no. 151, 977–989; Available online at https://doi.org/10.2307/2006208], and newly establish some closed formulas for some special values of the Bell polynomials of the second kind

Profiling and Identification of the Metabolites of Evodiamine in Rats using Ultra–Performance Liquid Chromatography with Linear Ion Trap Orbitrap Mass Spectrometer

Purpose: To develop a highly sensitive and specific ultra-performance liquid chromatography with linear ion trap Orbitrap mass spectrometer (UPLC-LTQ-Orbitrap) method to profile and identify the metabolites of evodiamine in rats.Methods: First, blood samples were collected after oral administration of evodiamine to rats (50 mg/kg). Next, the plasma samples were pretreated using a solid-phase extraction (SPE) method. Finally, all the samples were analyzed by ultra-performance liquid chromatography LTQ-Orbitrap mass spectrometry (UPLC-LTQ- Orbitrap) coupled with electrospray ionization source (ESI) in negative mode.Results: A total of 7 metabolites (2 phase I and 4 phase II metabolites, including 4 new metabolites, viz, 10-hydroxyevodiamine sulfate, 10-hydroxyevodiamine sulfate, 10-hydroxyevodiamine glucuronide and 3-hydroxyevodiamine glucuronide) as well as the parent drug itself , were detected and identified based on accurate mass measurements, fragmentation patterns, and chromatographic retention times. The in vivo metabolic reactions of evodiamine in rats were hydroxylation, hydroxylation + sulfate conjugation, and hydroxylation + glucuronidation.Conclusion: These results provide better understanding of the metabolism of evodiamine as well as strong indications of the effective forms of the drug in vivo.Keywords: Evodiamine, Ultra–performance liquid chromatography with linear ion trap-Orbitrap, Hydroxyevodiamine sulfate, Hydroxyevodiamine glucuronide, Metabolite